Molecular Formula | C22H33NO4 |
Molar Mass | 375.5 |
Density | 1.19±0.1 g/cm3(Predicted) |
Melting Point | 86~88℃ |
Boling Point | 554.2±50.0 °C(Predicted) |
Specific Rotation(α) | (Me2CO)-25.4 |
Flash Point | 289°C |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents. |
Vapor Presure | 2.52E-12mmHg at 25°C |
Appearance | Colorless needle crystal |
pKa | 8.90±0.70(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.555 |
MDL | MFCD11111456 |
Physical and Chemical Properties | White needle-like crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from stemona. |
HS Code | 29399990 |
Reference Show more | 1. Zhang Ning, Gao Xia, Zhou Yu, et al. Rapid analysis of chemical constituents in Xingbei Zhike granules by UPLC-Q-TOF-MS/MS [J]. Chinese Journal of Traditional Chinese Medicine, 2018, 43(22):4439-4449. 2. Liu Yuan, Dong Yunxia, Bai Jianlin, etc. Optimization of extraction process of Wuwei qingfei Guben capsule by multi-index comprehensive score-orthogonal test [J]. Chinese folk medicine, 2018, 29 (14):31-35. 3. Chen Xiaoxia, Zhang Xu, Shen Xiaoqing, etc. Study on the determination method of total alkaloids in the leaf [J]. Chemical Engineer, 2011(05):24-26. |
Overview | stemona alkaloids are the main characteristic components of stemonaceae plants, for the separation and identification of alkaloids in stemona has gone through a long process. The fat-soluble components of the genus stemona are mainly alkaloids. The earliest chemical studies began in Japan. As early as 1913, a kind of alkaloid was isolated from the wild. Subsequently, in the years from 1929 to 434, another Japanese scholar reported that stemona alkaloids, hexachine alkaloids and hexachisodine alkaloids were isolated from the roots of the racemates. Since then, domestic and foreign scholars have studied the chemistry and pharmacology of the plant, and found that the main component with pharmacological activity is alkaloid. In the early 30's through the degradation, oxidation, reduction and other chemical methods to determine the leaf base functional groups. Chinese chemist Zhu renhong made a more detailed study on the chemical composition of the vertical and the leaf of the leaf, and separated the vertical part of the base, that is, the original base and the leaf. |
preparation | a method for extracting the alkaloid of the leaf, comprising the following steps:(1) taking 2kg of Chinese herbal medicine, (2) refluxing with 4 L of 95% ethanol solution for 3 hours, extracting twice, and extracting;(3) taking the extract and concentrating to dryness;(4) the concentrated solution was eluted with D101 macroporous adsorption resin column (3kg) with a diameter of 12 μm and 3 liters of 40% methanol solution;(5) the collected parts containing the alkaloids were concentrated in 200ml of absolute ethanol, and 3ml of hydroiodic acid was added to form a salt. The crystals were cooled at 0 ° C. Overnight, and then filtered and dried to obtain 7g of the extracts of the alkaloids. |
Use | it can inhibit a variety of pathogenic bacteria and skin fungi; Prevent influenza Virus; Kill rodenticides, head lice, body lice, pubic lice, Animal lice, bedbugs, fly maggots, etc.; Have a relaxation effect on the spasm of isolated guinea pig bronchial smooth muscle induced by histamine. for content determination/identification/pharmacological experiments. Pharmacological Efficacy: moistening the lung and relieving cough, insecticidal. For the new long Cough, lung, Cough, pertussis; External for head lice, body lice, furunculosis, pruritis. |